Two kids crushed to death as school bus falls into gorge

DEHRADUN: Two school kids, six to seven years old, were crushed to death and four others seriously injured after a school mini bus fell into a gorge in Haridwar district of Uttarakhand on Thursday.

Haridwar SSP Arun Kumar Joshi said incident occurred at 8.10 am as the bus driver, Sunil, was trying to overtake a tempo. Joshi said that in the process the speeding bus overturned and fell into a gorge.

Joshi said these two kids, Diwanshu (6) and Radhika (7), died due to serious injuries on way to the hospital.

Sunil ran away from the spot. He was later arrested by police near Roorkee. Joshi said police have registered cases against driver on charge of rash and negligence driving.

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Study: Fish in drug-tainted water suffer reaction


BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.


It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.


The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.


"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.


Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.


"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."


Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.


They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.


The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.


The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.


The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.


The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.


"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."


Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.


Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.


It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.


Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."


Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.


The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.


Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.


Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.


___


Online:


Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html


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Ovation for Pope Benedict at final public mass


VATICAN CITY (Reuters) - A capacity crowd in St Peter's Basilica gave Pope Benedict a thunderous standing ovation on Wednesday at an emotional last public Mass before he resigns at the end of the month.


"Thank you. Now, let's return to prayer," the 85-year-old pontiff said, bringing an end to several minutes of applause that clearly moved him. In an unusual gesture, bishops took off their mitres in a sign of respect and a few of them wept.


One of the priests at the altar, which according to tradition rests above the tomb of St Peter, took out a handkerchief to dry his tears.


The Mass was moved to St Peter's from a venue in Rome so more people could attend. Hundreds of others waited outside.


Hours earlier in the Vatican's modern audience hall, a visibly moved Benedict tried to assure his worldwide flock, saying he was confident his decision to step down would not hurt the Church.


The Vatican, meanwhile, announced that a conclave to elect his successor would start sometime between March 15 and March 20, in keeping with Church rules about the timing of such gatherings after the papal see becomes vacant.


"Continue to pray for me, for the Church and for the future pope," he said in unscripted remarks at the start of his weekly general audience, his first public appearance since his shock decision on Monday that he will step down on February 28.


It was the first time Benedict, 85, who will retire to a convent inside the Vatican, exchanging the splendor of his 16th century Apostolic Palace for a sober modern residence, had uttered the words "future pope" in public.


Church officials are still so stunned by the move that the Vatican experts have yet to decide what his title will be and whether he will continue to wear the white of a pope, the red of a cardinal or the black of an ordinary priest.


His voice sounded strong at the audience but he was clearly moved and his eyes appeared to be watering as he reacted to the thunderous applause in the Vatican's vast audience hall, packed with more than 8,000 people.


In brief remarks in Italian that mirrored those he read in Latin to stunned cardinals on Monday he appeared to try to calm Catholics' fears of the unknown.


He message was that God would continue to guide the Church.


EXAMINATION OF CONSCIENCE


"I took this decision in full freedom for the good of the Church after praying for a long time and examining my conscience before God," he said.


He said he was "well aware of the gravity of such an act," but also aware that he no longer had the strength required to run the 1.2 billion member Roman Catholic Church, which has been beset by a string of scandals both in Rome and round the world.


Benedict said he was sustained by the "certainty that the Church belongs to Christ, who will never stop guiding it and caring for it" and suggested that the faithful should also feel comforted by this.


He said that he had "felt almost physically" the affection and kindness he had received since he announced the decision.


When Benedict resigned on Monday, the Vatican spokesman said the pontiff did not fear schism in the Church after his resignation.


Some 115 cardinals under the age of 80 will be eligible to enter a secret conclave to elect his successor.


Cardinals around the world have already begun informal consultations by phone and email to construct a profile of the man they think would be best suited to lead the Church in a period of continuing crisis.


The conservative Benedict has appointed more than half of the cardinals who will elect his successor so it is unlikely the new man will tamper with any teachings such as the ban on artificial birth control or women priests.


But many in the Church have been calling for the election of someone who they say will be a better listener to other opinions in the Church.


The likelihood that the next pope would be a younger man and perhaps a non-Italian, was increasing, particularly because of the many mishaps caused by Benedict's mostly Italian top aides.


Benedict has been faulted for putting too much power in the hands of his friend, Secretary of State Cardinal Tarcisio Bertone. Critics of Bertone, effectively the Vatican's chief administrator, said he should have prevented some papal mishaps and bureaucratic blunders.


ILL-SERVED POPE


"These scandals, these miscommunications, in many cases were caused by Pope Benedict's own top aides and I think a lot of Catholics around the world think that he was perhaps ill-served by some of the cardinals here," said John Thavis, author of a new book, The Vatican Diaries.


Benedict's papacy was rocked by crises over sex abuse of children by priests in Europe and the United States, most of which preceded his time in office but came to light during it.


His reign also saw Muslim anger after he compared Islam with violence. Jews were upset over rehabilitation of a Holocaust denier. During a scandal over the Church's business dealings, his butler was accused of leaking his private papers.


"When cardinals arrive here for the conclave ... they are going to have this on their mind, they're going to take a good hard look at how Pope Benedict was served, and I think many of them feel that the burden of the papacy that finally weighed so heavy on Benedict was caused in part by some of this in-fighting (among his administration)," Thavis told Reuters.


Vatican spokesman Father Federico Lombardi urged the faithful to remain confident in the Church and its future.


"Those who may feel a bit disorientated or stunned by this, or have a hard time understanding the Holy Father's decision should look at it in the context of faith and the certainty that Christ will support his Church," Lombardi said.


Lombardi said that on his last day in office, Benedict would receive cardinals in a farewell meeting and after February 28 his ring of office, used to seal official documents, would be destroyed just as if he had died.


(Reporting by Philip Pullella; Editing by Giles Elgood)



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Tennis: Nadal out of Brazil Open doubles over knee fear






SAO PAULO: Rafael Nadal will not play his scheduled doubles match at the Brazil Open Wednesday because of "knee overuse", organisers said.

But they added that the Spanish star intends to play his opening singles match Thursday against Brazilian Joao Souza.

World number five Nadal had been scheduled to team up with Argentina's David Nalbandian in a second-round encounter against Argentine Horacio Zeballos and Austrian Oliver Marach on Wednesday.

Former world number one Nadal only returned to the tour in Chile last week, where he lost in the final, after a seven-month injury absence.

"The conditions are very difficult. The court is not in the best condition and the ball is very difficult to control," Nalbandian told a press conference.

Nalbandian and Nadal won a hard-fought match 6-3, 3-6, 11-9 against Spaniards Pablo Andujar and Guillermo Garcia-Lopez on the court late Tuesday.

"It's too bad I cannot play the doubles after the match Rafa and I had (yesterday)," the Argentine said. "But he (Nadal) has to take care of himself and prepare for a long and hard year".

At a press conference Tuesday, Nadal complained about having to play so many hardcourt events

"That is a theme among the players and doctors," he said.

While conceding that reducing the number of events on hard surface was not possible at this time, he added: "I think that the ATP has to work to think of how to lengthen tennis players' careers."

"Can you imagine football players playing on cement?" he added.

"I am a bit tired after a hard week in Chile. But it was positive. The process of recovery follows its course," Nadal also said. "As always I come here to do the best possible and hope that things turn out all right."

Asked when he expected to be 100 per cent fit, he responded: "I cannot know the future. If my knee allows, I will do everything possible to be at my best."

"I am a player who plays with a lot passion, a lot of energy. I suppose that does not help the knee."

"My long-term objective is to be in Brazil in 2016 (for the Rio Summer Olympics). I am going to work to arrive in good condition at what are likely to be my last Olympics," he said.

Considered by many to be the best ever claycourt player, seven-time French Open champion Nadal was back in Chile last week for the first time since a surprise second-round exit at Wimbledon in June.

The world number five lost the singles and doubles finals in the Vina del Mar Open on Sunday.

- AFP/jc



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When loves turns into hate

Once, love was all about getting romantic. Now, it's about getting back. The number of cases of possessive lovers hacking mail accounts and spamming their ex-partners have soared. "Creating fake profiles and indiscriminate sending of mails for harassment are complaints that we often encounter," admits a senior police officer in Bangalore, the country's IT capital which regularly sees such cases.

A recent survey, conducted by online security firm McAfee, which covered 967 respondents in Chennai, Mumbai and Delhi and a few other cities, found that more than 26% of the 200-odd ex-lovers interviewed in Chennai admitted to have threatened their former partners of making public their intimate pictures and messages. What's more, all of them carried out the threats. In Mumbai, more than 34% of the respondents said they had faced these threats from their ex-partners, and that 77% had carried out the threats. In Delhi, the rate of those who had received such threats was 31%, with 71% carrying out the threats. In fact, the survey which was replicated in nine other countries, found that Indian respondents ranked the highest, in terms of having behaved in a way so as to disturb or damage the relationship of the ex-partner and their new partner.

Many attribute this retaliatory behavior to the way relationships are structured now in an increasingly online environment where every moment of your partner's life can be tracked. "Everything about dating has changed in the age of social networking," says Rushali Naik, a postgraduate student. "Gone are the days when one could admire someone from a distance and daydream about them. Now, we have so much access to the other person's life that it's frightening."

And once the relationship turns sour, it just takes a few clicks to turn life hell for the person you once loved. BN Gangadhar, professor of psychiatry, Nimhans, says that it's a dangerous trend. "An adverse post on Facebook can even send someone into depression."

A flip side of these heartbreaks and the resultant hatred is that a number of websites have sprouted to provide ex-lovers an outlet. A few like Neverlikeditanyway.com are e-commerce driven which allow you to sell gifts given by your ex in order to let go of the pain. Lucknow-based Richa who was recently dumped by her boyfriend is planning to sell a ruby ring gifted by him. "Whenever I see the ring, it just reminds me on how he cheated on me. It will be a catharsis getting rid of it."

(Reports by Arun Dev in Bangalore; M Ramya in Chennai and Priyangi Agarwal in Lucknow)

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Clues to why most survived China melamine scandal


WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.


In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?


A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.


The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.


The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.


A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.


Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.


Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.


More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.


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Ship Stranded: Love Boat to Horror Honeymoon













A Texas couple's fantasy wedding quickly turned into a nightmare honeymoon when the fire-damaged Carnival Cruise ship carrying them became stranded in the Gulf of Mexico.


Rob Mowlam, 37, and Stephanie Stevenson, 27, of Nederland, Texas, got married on the Carnival Triumph on Saturday. The four-day cruise was meant to be back to shore on Monday, but was left disabled by an engine fire on Sunday.


The ship is being slowly towed to shore and is expected to dock in Mobile, Ala., on Thursday if weather permits. The vessel is without air conditioning, many working toilets and some restaurant service. Passengers, many who are sleeping in tents on deck, have told ABC News the smell on the ship is foul.


That is the honeymoon setting for Mowlam and Stevenson.


"[Rob Mowlam] had been with his girlfriend, or fiance, for a long period of time and they just took the next step," Mowlam's brother James Mowlam III told ABCNews.com. "The captain is the king of the world when they're on the boat and he hitched them up."


James Mowlam said he was shocked when he heard about the stranded boat and the increasingly dire conditions on the ship.


"It is an atrocious scene to be subjected to," he said.


Mowlam said he has not been able to communicate with his brother, but that his father has had sporadic communication with him.


"It would be my guess that this would probably not be on anyone's great list of memorable wedding experiences," Mowlam said with a laugh. "Although, my mom told him that she was hoping they had a memorable wedding and I think this would classify as a memorable wedding experience."






Lt. Cmdr. Paul McConnell/U.S. Coast Guard/AP Photo











Carnival Cruise Ship Stranded for Third Day Watch Video









Carnival Cruise Ship Stranded off Yucatan Peninsula Watch Video









Cruise Ship Stranded Without Power in Gulf of Mexico Watch Video





The bride's brother, Justin Davis, told ABCNews.com that his sister works for a doctor's office and the cruise was a gift from the doctor to the staff.


Davis has not been able to speak to Stevenson but said that her two young sons are being cared for by her mother. He said his sister is tough and he guesses she's probably not scared.


"She might be a little aggravated at the situation, but I'd say she's [probably] handling it really well," he said.


Others on the ship do not seem to be handling the situation so well.


Elderly and disabled passengers aboard the ship are struggling to cope with the worsening conditions, according to at least one passenger.


"Elderly and handicap are struggling, the smell is gross," passenger Ann Barlow text-messaged ABC News overnight. "Our room is leaking sewage."


The head of Carnival Cruise Lines said the British-U.S.-owned company was working hard to ensure the thousands of passengers stranded on the disabled ship were as comfortable as possible while the vessel was being towed to a port in Alabama.


"I need to apologize to our guests and to our families that have been affected by a very difficult situation," Carnival Cruise Lines president and CEO Gerry Cahill said at a news conference Tuesday evening.


It was the first time since a fire erupted in Triumph's engine room Sunday, knocking out its four engines, that a company representative had spoken publicly. The Triumph, with roughly 4,200 people on board, was left bobbing like a 100,000-ton cork for more than 24 hours. Giant sea-faring tugboats then hooked up to the ship and began towing the nearly 900-foot-long ship to land.


Carnival spokeswoman Joyce Oliva told The Associated Press Tuesday that a passenger with a pre-existing medical condition was taken off the ship as a precaution. Everyone else will likely have to weather conditions such as scarce running water, no air conditioning and long lines for food.


Back on land, passenger Barlow's 11-year-old twins told ABC News Tuesday they are worried as more passengers continue to talk about living with limited power and sanitation.






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17 gunmen dead in Thai military base attack

 





BANGKOK, Thailand: Scores of heavily-armed gunmen stormed a military base in unrest-plagued southern Thailand, an army spokesman said on Wednesday, in a major assault that left at least 17 militants dead.

"Some 100 fully armed militants stormed the base, where there were 60 marines," Colonel Pramote Promin, southern army spokesman, told AFP.

He said the attack, one of the most ambitious in several years of violence in Thailand's three southernmost provinces, had left at least 17 assailants dead. No military casualties were reported.

- AFP/de




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'I have emerged stronger after blast'

PUNE: AmrapaliChavan, who suffered severe burns in the German Bakery blast, says the incident made her mentally and physically strong.

"I have become a strong woman now. It taught me some bitter lessons as well as some rewarding ones. The realisation that I am a fighter and have a strong will power dawned upon me after I fought back. I did so because I wanted to live. I have also realised that people whom we rely upon the most may also turn their backs on us when we need them. I harbour no grudges as I have understood the true meaning of life and how invaluable it is," said Amrapali.

Amarapali, 27, is currently giving final touches to her book 'Ek Cup Coffee at German Bakery' in which she talks about her exper ences. "A few publishers have approached me for publishing the book," she said.

Amrapali says her book will hit the stands within three months.

"It is the story of a city as well as a woman whose life changed drastically after the blast. It is a story that depicts how a woman had to struggle to tide over the fear that took hold of her after the blast - the fear to come out of a shell, the fear to tread roads she would otherwise walk on so confidently, the fear to come to terms with one's own self, the fear of becoming a liability, the fear of not getting societal acceptance... It is a story of how the woman faced and eventually overcame all these manifestations of fears," said Amrapali.

There is still a long way to go but I am ready to take life as it comes, said the confident woman.

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IBM puts supercomputer to work on cancer






WASHINGTON: IBM is putting its Watson supercomputer to work fighting cancer, in what is described as the first commercial program of its kind to use "big data" to help patients with the disease.

The US computing giant last week unveiled its initiative with health insurer WellPoint and Memorial Sloan-Kettering Cancer Center in New York.

The supercomputer, which gained fame by defeating two human champions in the "Jeopardy!" quiz show, has been sifting through some 600,000 pieces of medical evidence, two million pages of text from 42 medical journals and clinical trials in oncology research.

This can speed up the way data is analysed to make the best diagnosis and find the optimal treatment, says Craig Thompson, Sloan-Kettering's president.

"It can take years for the latest developments in oncology to reach all practice settings," Thompson said.

"The combination of transformational technologies found in Watson with our cancer analytics and decision-making process has the potential to revolutionise the accessibility of information for the treatment of cancer in communities across the country and around the world."

IBM first announced plans to work with WellPoint in 2011, and last year began receiving data from the New York research hospital which specialises in cancer.

The first application will work with 1,500 lung cancer cases, where clinicians and analysts are training Watson to extract and interpret physician notes, lab results and clinical research.

The Maine Center for Cancer Medicine and Westmed Medical Group will be two centres testing the service and providing feedback to WellPoint, IBM and Memorial Sloan-Kettering.

"IBM's work with WellPoint and Memorial Sloan-Kettering Cancer Center represents a landmark collaboration in how technology and evidence based medicine can transform the way in which health care is practiced," said Manoj Saxena at IBM.

"These breakthrough capabilities bring forward the first in a series of Watson-based technologies, which exemplifies the value of applying big data and analytics and cognitive computing to tackle the industry's most pressing challenges."

The program is being commercialised under the name Interactive Care Insights for Oncology, powered by Watson.

Watson, named after IBM founder Thomas Watson, can ingest tens of million pages of data in just seconds.

- AFP/jc



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